Human Primodial Germ Cell database
hPGCdb dedicates to collecting, analyzing, visualizing high-throughput sequencing data in the field of human
primordial germ cells. A unified framework, and multi-level analyses were performed to provide user-friendly ways to
explore the bulk-transcriptome, single-cell transcriptome, chromatin accessibility, and protein-DNA interaction
characteristics in human primordial germ cells.

Bulk RNA-seq RNA-seq samples consist of hESCs, iMeLCs, hPGCLCs, hPGCLC aggregates, and hPGCs. Both of male & female, in vivo and in vitro, WT and Gene-KO samples are included

ATAC-seq Both in vitro and in vivo samples from hESCs to hPGCLCs/hPGCs, together with several somatic cell types, are visualized as tracks.



Chip-seq The ChIP-seq samples including TFAP2C, H3K27ac, CTCF, MED1, OCT4, PAX5, PRDM1, and SOX15.




Single cell RNA-seq hPGCdb provides an integration of germline lineage cells from multiple studies. This merged germline lineage includes hESCs, hiPSCs, iMeLCs, day1-4hPGCLCs, week7-16 female ovaries, week17-18 male testis.
Statistics

Bulk RNA-seq Sample

581

Single Cell

300,000+

ATAC/ChIP-seq Sample

98

Merged germline lineage Cell

47,000+